Adrenal gland – part 1. (~ 21 min)

Sort adrenal gland zones and hormones that are produced by that zone:

This zone of adrenal cortex produces which of the following hormones?

Blood pressure in 17α-hydroxylase deficiency is ____________

• elevated midnight salivary cortisol

• serum ACTH is high

• no suppression of cortisol level on high-dose dexamethasone suppression test

Which of the following is the diagnosis?

All congenital adrenal enzyme deficiencies can be presented with skin hyperpigmentation. Which of the following is a cause of skin hyperpigmentation?

Let`s learn primary adrenal insufficiency types:

Pick types of congenital adrenal hyperplasia which can be associated with precocious puberty:

Sort elements:

Which is the name of the missed enzymes?

Androstenedione in 17α-hydroxylase deficiency is ___________

• female fetus has ambiguous genitalia and/or female virilization

• blood pressure is low

• K+ is high

Which of the following is a cause?

• adolescent female presented with excessive body hair growth, acne, deepening of the voice

According to additional symptoms presented below which of the following is a cause?

Proopiomelanocortin is a precursor of:

The most common causes of Addison disease is the __________

Pick laboratory findings in primary hyperaldosteronism (Conn syndrome):

Let`s learn the diagnostic steps of the cause of Cushing syndrome:

• Elevated blood pressure

• Decreased renin

• Increased aldosterone

Which of the following is a diagnosis?

All patients who take exogenous glucocorticoids have __________

Pick metabolic actions of cortisol:

• no suppression of cortisol level on low-dose dexamethasone suppression test

• serum ACTH is high

• no suppression of cortisol level on high-dose dexamethasone suppression test

Which of the following is the diagnosis?

Mineralocorticoid effects (increased blood pressure and low serum K+) in patients with 11β-hydroxylase is due to the high levels of _____

Epinephrine, glucagon and cortisol cause insulin resistance by which of the following mechanisms?

• hypotension

• fatigue

• hyperkalemia

Which of the following is a most likely cause of hyperpigmentation?

Pick screening tests for Cushing syndrome:

Pick signs of aldosterone deficiency:

Which of the following tests allows to diagnose Waterhouse-Friderichsen syndrome?