Сhemotherapy 1
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Question 1 of 12
1. Вопрос
Which of the following drugs helps to prevent the occurrence of dilated cardiomyopathy caused by doxorubicin?
ВерноНеверно -
Question 2 of 12
2. Вопрос
Sort drugs and mechanism of action:
Сортировать элементы
- Hyperstabilize polymerized microtubules
- Inhibit thymidylate synthase
- Add an alkyl group to the guanine base of the DNA and makes strands unable to uncoil and separate
- Inhibit dihydrofolate reductase
- Purine analogs, inhibit de novo purine synthesis
- Inhibit β-tubulin polymerization into microtubules
- Inhibit ribonucleotide reductase
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Paclitaxel
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5-fluorouracil
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Carmustine, lomustine; Busulfan; Cyclophosphamide, Ifosfamide
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Methotrexate
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Azathioprine; 6-mercaptopurine
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Vincristine; Vinblastine
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Hydroxyurea
ВерноНеверно -
Question 3 of 12
3. Вопрос
Additional use of leucovorin is indicated in combination with:
Сортировать элементы
- Methotrexate
- 5-fluorouracil
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Leucovorin is added to reduce myelosuppression
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Leucovorin is added to enhance cytotoxic effects
ВерноНеверно -
Question 4 of 12
4. Вопрос
Both of these drugs inhibit DNA polymerase as chain terminators. Sort drugs:
Сортировать элементы
- Purine analog
- Pyrimidine (cytosine) analog
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Cladribine
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Cytarabine
ВерноНеверно -
Question 5 of 12
5. Вопрос
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hematuria
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dysuria
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suprapubic pain
Which of the following can potentially be a cause?
ВерноНеверно -
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Question 6 of 12
6. Вопрос
Which of the following is a monoclonal antibody against vascular endothelial growth factor?
ВерноНеверно -
Question 7 of 12
7. Вопрос
Which of the following cytostatics arrest cell cycle at G2/M phase?
ВерноНеверно -
Question 8 of 12
8. Вопрос
Sort side effects:
Сортировать элементы
- Vinblastine
- Vincristine
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Myelosuppression
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Peripheral neuropathy
ВерноНеверно -
Question 9 of 12
9. Вопрос
Vemurafenib is used for the treatment of ________
ВерноНеверно -
Question 10 of 12
10. Вопрос
Sort cancer drugs and cell cycle:
Сортировать элементы
- G2-M
- Mitosis
- Cell cycle–independent
- S-G2
- S phase
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Bleomycin
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Vincristine, vinblastine; Paclitaxel; Eribulin
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Carmustine, lomustine; Busulfan; Cyclophosphamide, Ifosfamide; Cisplatin
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Etoposide, teniposide, irinotecan, topotecan
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Cladribine; Cytarabine; 5-fluorouracil; Methotrexate; 6-mercaptopurine; Azathioprine
ВерноНеверно -
Question 11 of 12
11. Вопрос
Sort functions of the products of the following genes:
Сортировать элементы
- Receptor tyrosine kinase
- Transcription factor
- GTPase
- Non-receptor (cytoplasmic) tyrosine kinase
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RET; HER2/neu (c-erbB2); ALK
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MYCL1; N-myc; c-MYC
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KRAS
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BCR-ABL; JAK2
ВерноНеверно -
Question 12 of 12
12. Вопрос
Ototoxicity and nephrotoxicity is a side effect of ________
ВерноНеверно